Product Name :
NM23 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
AWD antibody AWD, drosophila, homolog of antibody GAAD antibody Granzyme A activated DNase antibody Granzyme A-activated DNase antibody GZMA activated DNase antibody Metastasis inhibition factor NM23 antibody NB antibody NBS antibody NDK A antibody 展开
Function :
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease-hypersensitive elements at positions 142 to 115 of the human C-Myc promotor.5-Bromo-2-(trifluoromethoxy)pyridine Purity
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within N-terminal human NM23.2-Chloro-5-hydroxyisonicotinic acid web
Species reactivity:
Human, Mouse
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3073409
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33403601 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
17/19 kDa
Positive control :
Hela, HepG2, MCF-7, Jurkat.